Gene Information

Gene Symbol

This is the official gene symbol as approved by the HUGO Gene Nomenclature Committee.

Gene Name

Official Gene Name as approved by the HUGO Gene Nomenclature Committee.

Alt Names

Alternative gene names as defined by NCBI Entrez Gene and/or Stanford SOURCE database.

Chr.

Human Chromosome #

Chr-Band

Chromosomal band as defined by NCBI Entrez Gene.

DNA position

This is the beginning gene position on the human genome sequence as defined in the UCSC Genome Browser, Human March 2006 (hg18) Assembly.

Locus Link number

Numerical Only. This is the Entrez gene ID as defined by NCBI Entrez Gene.

Unigene Cluster number

This is the Unigene number (Hs.NNNN) as defined by NCBI Unigene.

Rep Seq

This field is a representative sequence for this gene.

Study Information

Broad Phenotype (Disease)

This is the general disease or phenotypic classification.

Narrow Phenotype

This is for sub-phenotype, endo-phenotype, locus specific phenotype, or molecular phenotype.

Disease Class

There are 19 disease classes defined currently: aging, cancer, cardiovascular, chemdependency, developmental, hematological, immune, infection, metabolic, mitochondrial, neurological, normalvariation, pharmacogenomic, psych, renal, reproduction, vision, other or unknown (if the author did not identify a disease class).

Assoc? YorN

This is a simple yes or no. In the paper, is the gene associated with a phenotype (Y) or a lack of association (N). GAD will display nothing (Null) if the author did not specify either way.

P-value

The best P-value for that allele. There may be a number of P-values under different assumptions or models. We are looking for the best P-value.

Reference

The full reference for the study

PubMed ID

The PubMed unique identifier number (UID number). This number is embedded in the URL for the abstract in PubMed. For example, the PubMed IUD is 12438686 for the following entry.... http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12438686&dopt=Abstract

Population

The ethnic group of the study.

Study size Cases

Generally, the patient class. Many studies(not all) will be case-control studies. Study size A is for the patients. If this exactly doesn't apply, do your best.

Study Size Controls

Generally, the control class. Many studies (not all) will be case-control studies. Study size B is for the controls. If this exactly doesn't apply, do your best.

Total study size

The patients and controls added together.

PCR protocol

Short text description of the PCR protocol used for that allele.

Polymorphism class

General class of polymorphism.

Allele (Authors description)

This is a text description of the allele under study in the author's own words.

Allele functional effect

Text description of the effect of the polymorphism. This can be at any level, transcriptional, protein, disease, etc.

Allele figure

A link to a figure of the allele. e-mail beckerk.nia.nih.gov if you know of| a useful figure.

Gene Comment

This is for gene based comments. Such as, I work on APOE and I am having trouble PCRing up APOE 4. etc. etc.

Submitter Information

Submitter name

Submitter name. Anyone can submit, you don't have to be an author on the original study.

Submitter e-mail

Submitter e-mail.| You don't have to be a author on the paper to submit a record.

Link Information

PubMed

The URL of the single PubMed abstract for this study.

Locus Link

NCBI Locus Link URL for this gene.

Gene Cards

Gene Cards URL for this gene.

Pathway search

Pathway database. e-mail beckerk.nia.nih.gov

if you know of a good pathway image for this gene.

NCBI SNP

A link to NCBI SNP database for that gene.

SNPedia

A link to SNPedia for that gene.

PubMed + Gene + Disease

Pre-set PubMed search for this GENE and this DISEASE.

PubMed + Gene + polymorphism

Pre-set PubMed search for this GENE and POLYMORPHISM.

MAPV

Link to NCBI map view.

UCSC

Link to UCSC genome browser.

Ensembl

Link to Ensembl Genome Browser e!.

Expert Name

Expert name. Such as: Dr. Ashley C. Jones.

Title

Title of the expert. Such as: Director.

Affiliation

Affiliation of the expert. Such as: Cambridge University Clinical Immunology department.

Type of Expert

Type of expert: Such as: gene polymorphism typing.

Web Site

The URL to a web site of your choice.